Forskolin is an ingredient found in the Indian coleus plant, also known as Coleus forskohlii. It is a labdane diterpene that is currently very popular as a nutritional supplement, predominantly in the body building circles. The ability to raise the levels of cyclic adenosine monophosphate, cAMP, by deploying the enzyme adenylyl cyclase in the cAMP dependent pathway, made forskolin very important. Further benefits of forskolin include reduction of urinary tract infections, in connection with rolipram inhibition of colon cancer spreading, stimulation of proper tanning response with increased skin resistance to sun burns, reduction of intraocular pressure in glaucoma cases and apparently assistance in weight loss programs. Forskolin was observed to increase bone and lean mass as well as testosterone levels in clinical trials conducted with human test subjects.