Bioperine or black pepper, which is a common spice, has medicinal properties. It is a tropical plant and India is the largest producer of Piper Nigrum. It possesses anti-bacterial and anti-inflammatory properties. It acts as an antioxidant agent also. Black Pepper contains essential oil, which acts against intestinal flatulence and also stimulates sweating and urination. The essential oil found in Piper Nigrum stimulates stomach cells to produce HCl acid, which helps in digestion. Piper Nigrum also helps in absorption of certain essential micronutrients like coenzyme Q-10, beta-carotene and EGCG. Pepper has its contribution in Ayurvedic medicines also. Pepper seeds are used to prepare sinusitis relieving medicines. It also used for sore throat and dry cough.

Caffeine is of course a major component of every day drinks such as tea and coffee and is also included in Tight. It is claimed that over 70% of the American population take more than 300 milligrams daily. As well as in familiar drinks it is used in energy drinks such as Red Bull as well as in many over the counter analgesics and other medication. Medically it is a as trimethylxanthine, useful as a heart stimulant and it also works as a mild diuretic. It works in the same way as certain drugs, the amphetamines, cocaine, and heroin, all of which work on the action of the brain although in a milder way, and like them it is addictive.

Green Tea Extract is currently being promoted by the health conscious community as a weight loss product, which does not do this incredible concoction of helpful ingredients justice. Many green tea extracts nowadays exclude caffeine, to avoid the associated side effects and lower the ingestion of this legal addictive stimulant. The main characteristic of the green tea extract should be the antioxidative effect, which surpasses Vitamin C twentyfold. But the other traits are not to be forgotten, it is anti-inflammatory, anti-carcinogen and anti-radiation. The unique combination of green tea catechins, derivatives of apicatechin, and flavonoids, which belong to the same family, are proven scavengers of free radicals and an unavoidable addition to any dietary supplement combination, body building or weight loss as the target objective.

Sclareolide, which is thought to increase cAMP (cyclic adenosine monophosphate) levels in the body through the stimulation of the "adenylate cyclase" (AC) enzyme. This stimulation is believed to help activate increased fat burning.

Synephrine or oxedrine is a drug derived from bitter orange or Citrus aurantium. It is an aromatic compound with the systematic name 4-[1-hydroxy-2-(methylamino)ethyl]phenol which indicates that it has an attached hydroxyl group at para position and a methyl amino group at another position. It is not one of those compounds on which an extensive scientific study has been done. However, it has some positional isomers such as the neosynephrine as well as other compounds. Studies indicate that it could act as a Beta-3 adrenergic receptor which means that if taken as a supplement it enhances the breakdown of fat to release energy and also increases heat production in the muscles.

Synthetic Guggulsteroneswere first intended for use as a drug and is now used as a weight loss product and weight management product with the possibility of some side effects. More studies need to be done on this.

Vinpocetine, a derivative alkaloid of vincamine, is actually semi synthetic in nature. It is an extract from the It is an extract from the periwinkle vinca minor. Vinpocentine is used because it has neuroprotective effects and also helps in enhancing the cerebral blood flow. In Eastern Europe, it is also used as a drug to treat cerebrovascular disorders along with age related memory impairment. It is also extensively marketed as a supplement for vasodilation. It is also used to improve the memory since it plays the role of a nootropic. Vinpocentine is therefore used in supporting brain function. It helps in enhancing concentration and memory by activating cerebral metabolism. In the body building world, vinpocetine is often used a vasodilator. However, no research has been done so far on the effect of vinpocentine in the body building.

Yohimbe- Basically a tree bark, Yohimbe is rich in pharmacologically active chemicals. It is commonly found in products developed for body building and enhancing male performance. The use of Yohimbe causes serious side effects too that include renal failure, seizures and in very rare cases, even death. Individuals suffering from low blood pressure, heart disease, liver or kidney disease, and diabetes should refrain from using any kind of Yohimbe supplements. Taking larger doses of Yohimbe can cause weakness, stomach disorders, fatigue, and nervous stimulation followed by paralysis. It is therefore important to avoid self-medication. Sometimes, side effects may arise even if small amounts of this supplement are taken, especially for prolonged periods. If you are already taking drugs for treating some health condition, it is best to avoid this supplement.